Streptococcus mutans Surface -Enolase Binds Salivary Mucin MG2 and Human Plasminogen
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چکیده
Matrix-assisted laser desorption ionization–time of flight mass spectrometry analysis identified enolase as a cell surface component of Streptococcus mutans, which was confirmed by enzyme-linked immunosorbent assay, Western blotting, and transmission electron microscopy. Surface enolase was demonstrated to bind to human plasminogen and salivary mucin MG2. The results suggested a role for enolase in S. mutans attachment, clearance, or breach of the bloodstream barrier.
منابع مشابه
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تاریخ انتشار 2004